Advair, Nicotrol, Teveten, Lovaza, Noxafil Drugs are off-Patent

An expired patent cannot be renewed. After the patent on a drug expires, any pharmaceutical company can manufacture a generic version of the drug and sell it. This helps the manufacturer of the generic incur only manufacturing cost avoiding the cost of original testing, development and marketing. 

A phenomenon called patent cliff arises when drugs go off-patent as a firm's revenues goes down since these products can be replicated and sold at much cheaper prices by competitors, opening opportunities for generic drug manufacturers.

All the generic products should be approved by FDA, which requires pharmaceutical companies to submit ANDA (for a therapeutic equivalent to an originally approved drug) for approval. Hatch-Waxman Act is a standardized U.S. procedure for recognition of generic drugs. FDA has also launched the Generic Initiative for Value and Efficiency (GIVE) to help modernize and streamline the generic drug approval process. More generic-drug options mean more cost-savings to consumers, as they are less expensive compared to the branded drugs.

The table below (sourced from Patent Maker) illustrates some of the medical devices and pharma patents that expired[i] in August 2014 along with the respective products covered.

U.S Patent Number	Category	Title	Owner/Assignee	Products Covered
5658549	Drug	Aerosol formulations containing propellant 134a and  fluticasone propionate	Glaxo Group Limited	Advair HFA
5661136		2-halo-2'-fluoro ARA adenosines as antinoplastic agents	N/A	Clolar
5656286		Solubility parameter based drug delivery system and method for altering drug saturation concentration	Noven Pharmaceuticals Inc	Combipatch
5658549		Aerosol formulations containing propellant 134a and fluticasone propionate	Glaxo Group Limited	Flovent HFA
5656722		A21-, B30 - modified insulin derivatives having an altered action profile	Sonafi Aventis Deutschland GMBH	Lantus
5656667		Fatty acid composition	Pronova Biopharma Norge AS	Lovaza
5656286		Solubility parameter based drug delivery system and method for altering drug saturation concentration	Noven Pharmaceuticals Inc	Minivelle
5656255		Composition to help stop smoking	MCNEIL AB	Nicotrol
5661151		Tetrahydrofuran antifungals	MERCK SHARP & DOHME CORP.	Noxafil
5654010		Composition for sustained release of human growth hormone	ALKERMES CONTROLLED THERAPEUTICS, INC.	Nutropin Depot
5656297		Modulated release from biocompatible polymers
5656296		Dual control sustained release drug delivery systems and methods for preparing same	CREDIT SUISSE AG	Procanbid
5656650		Angiotensin II receptor blocking compositions	N/A	Teveten
				Teveten HCT
5654301		Solubility parameter based drug delivery system and method for altering drug saturation concentration	RESEARCH CORPORATION TECHNOLOGIES, INC.	Vivelle-Dot
5656207	Medical Devices	Detecting or quantifying multiple analytes using labelling techniques	GOLDMAN SACHS BANK USA	Aptima Hpv Assay
5558097		Method for tachyarrhythmia detection	SORIN CRM SAS	Ovatio Crt-D 6750
5591218		Current limiter for implantable electronic device lead	Ela Medical
5657420	Electronics	Variable rate vocoder	N/A	Blackberry 8703e
5659569		Data burst randomizer
5657420		Variable rate vocoder		BlackBerry Bold 9650 Smartphone - 5.0
5659569		Data burst randomizer
5657420		Variable rate vocoder		BlackBerry Bold 9700 Smartphone - 5.0
5659569		Data burst randomizer
5657420		Variable rate vocoder		BlackBerry Curve 9300/9330 Smartphones Series - 6.0
5659569		Data burst randomizer
5942743		Portable automatic hand-supportable omnidirectional laser projection scanner with power conserving control system	METROLOGIC INSTRUMENTS, INC., METEOR HOLDING CORPORATION, OMNIPLANAR, INC.	Honeywell Fusion 3780 Scanner
6286760		Automatic hand-supportable laser projection scanner for omni-directional reading of bar code symbols within  a narrowly confined scanning volume
				Honeywell IS3480 QuantumE Laser Scan Engine
				Honeywell Orbit 7120
				Honeywell OrbitCG 7180
				Honeywell QuantumT 3580
6991167		Bioptical laser scanning system providing 360 DEG  of omnidirectional bar code symbol scanning coverage at a point of sale (POS) station		Honeywell Stratos 2400
7051922		Compact bioptical laser scanning system
7407103		Bioptical holographic laser scanning system
6991167		Bioptical laser scanning system providing 360 DEG  of omnidirectional bar code symbol scanning coverage at a point of sale (POS) station		Honeywell StratosH 2300
7051922		Compact bioptical laser scanning system
7407103		Bioptical holographic laser scanning system
5657420		Variable rate vocoder	N/A	HTC Smart phone
5659569		Data burst randomizer	N/A
5657420		Variable rate vocoder	N/A	HTC Touch diamond 2
5659569		Data burst randomizer	N/A
5657420		Variable rate vocoder	N/A	Motorola Sprint Mobile Broadband Smart Device
5659569		Data burst randomizer	N/A
5659122	Agriculture Seeds	Enhanced expression in plants using non-translated leader sequences	Monsanto Technology	Genuity Bollgard II cotton
5659122				Genuity Bollgard II with Roundup Ready cotton
5659122				Genuity Bollgard II with Roundup Ready Flex Cotton
5659122				Roundup Ready Alfalfa

Patent Marker is a database of products and patents, in which the patents that apply to each product are identified. Any registered user is free to add a product for marking. Patent Marker is an online tool that makes it easy for companies/patentees to mark their products and serve notice to the public of their ownership of inventions.

The database includes powerful search functionality that can be used to identify products and their related-patents, patent expiration date, number of litigations the patent is involved, etc. The database interfaces with MaxVal’s Litigation Databank and Assignment Database to retrieve litigation and current assignee information, respectively.

[i] Expected Expiration Date